Basilea Pharmaceutica - PharmaKB

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Company ReportsBasilea Pharmaceutica

Basilea Pharmaceutica

Basilea Pharmaceutica is a multinational specialty biopharmaceutical company headquartered in Basel, Switzerland. It was formed as a spin-off entity from the drug giant Hoffmann–La Roche in October 2000. It is engaged in the development of antibiotics, antifungals and oncology drugs for treatment of invasive aspergillosis and invasive mucormycosis. Basilea is publicly traded on the SIX Swiss exchange (SIX: BSLIN).

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Trade Name	Drug Name	Approved	Patent Expires	Indication
Cresemba	Isavuconazole	2015-10-15		Aspergillosis , Mucormycosis

Clinical Trials

Therapeutic Areas:

All

Classification:

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Approval:

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Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

healthy volunteers/patients

,

pharmacokinetics

,

hematologic neoplasms

,

,

renal insufficiency

,

,

,

invasive fungal infections

,

,

invasive candidiasis

,

,

,

,

myeloid leukemia acute

,

myeloid leukemia

diabetes mellitus

,

Antithrombin iii

streptococcal infections

,

rectal neoplasms

,

,

atrial fibrillation

,

mantle-cell lymphoma

,

multiple myeloma

,

plasma cell neoplasms

,

,

central nervous system neoplasms

,

nervous system neoplasms

,

colonic neoplasms

,

streptococcus agalactiae

,

breast neoplasms

,

,

,

ankylosing spondylitis

,

spondylarthritis

,

,

non-small-cell lung carcinoma

,

,

prostatic neoplasms

,

psoriatic arthritis

,

meningococcal infections

,

,

,

bcr-abl positive chronic myelogenous leukemia

,

,

sickle cell anemia

,

,

renal cell carcinoma

,

,

,

vision disorders

,

,

,

meningococcal meningitis

,

,

thrombocytopenia

,

,

neuroendocrine tumors

,

,

myeloid leukemia

,

ovarian neoplasms

,

human influenza

,

myelodysplastic syndromes

,

,

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

b-cell chronic lymphocytic leukemia

,

lymphoid leukemia

,

hepatocellular carcinoma

,

carcinoid tumor

,

malignant carcinoid syndrome

,

serotonin syndrome

,

,

hypercholesterolemia

,

hyperlipoproteinemia type ii

,

homozygous familial hypercholesterolemia

,

chronic obstructive pulmonary disease

,

,

obstructive lung diseases

,

gastrointestinal stromal tumors

,

philadelphia chromosome

,

ovarian epithelial carcinoma

,

axial spondyloarthritis

,

allergic rhinitis

,

,

allergic rhinitis seasonal

,

graft vs host disease

,

pituitary acth hypersecretion

,

acth-secreting pituitary adenoma

,

rheumatoid arthritis

,

,

,

,

,

,

haemophilus influenzae

,

non-hodgkin lymphoma

,

b-cell lymphoma

,

,

hodgkin disease

,

,

,

giant cell arteritis

,

polymyalgia rheumatica

,

follicular lymphoma

,

pancreatic neoplasms

,

,

myeloid leukemia chronic-phase

,

neuroendocrine carcinoma

,

,

,

essential hypertension

,

systolic murmurs

,

multiple sclerosis

,

neoplasm metastasis

,

chronic progressive multiple sclerosis

,

,

small cell lung carcinoma

,

merkel cell carcinoma

,

polyomavirus infections

healthy volunteers/patients

,

cholangiocarcinoma

,

,

urologic neoplasms

,

transitional cell carcinoma

,

hepatocellular carcinoma

,

healthy volunteers/patients

,

hepatic insufficiency

,

esophageal neoplasms

,

,

,

small cell lung carcinoma

,

pancreatic ductal carcinoma

,

multiple myeloma

,

plasma cell neoplasms

,

bronchiolitis obliterans syndrome

,

congenital abnormalities

,

chromosome aberrations

,

brain stem neoplasms

,

chronic hepatitis c

,

chronic hepatitis

,

,

,

medulloblastoma

,

,

,

choroid plexus neoplasms

,

primitive neuroectodermal tumors

,

,

,

neuroepithelial neoplasms

,

ganglioneuroblastoma

,

neuroectodermal tumors

,

phenylketonurias

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

nasopharyngeal carcinoma

,

ureteral neoplasms

,

pelvic neoplasms

,

adenoid cystic carcinoma

,

metabolic syndrome

,

follicular lymphoma

,

,

pancreatic neoplasms

,

kidney neoplasms

,

,

prostatic neoplasms

,

,

,

head and neck neoplasms

,

neurofibromatoses

,

,

liver neoplasms

,

,

,

neurofibromatosis 1

,

plexiform neurofibroma

,

systemic scleroderma

,

diffuse scleroderma

,

b-cell chronic lymphocytic leukemia

,

,

hematologic neoplasms

,

endometrial neoplasms

,

neuroendocrine carcinoma

,

central nervous system neoplasms

,

ovarian neoplasms

,

mantle-cell lymphoma

,

urinary bladder neoplasms

,

squamous cell carcinoma

,

uterine cervical neoplasms

,

myelodysplastic syndromes

,

non-hodgkin lymphoma

,

nervous system neoplasms

,

hypereosinophilic syndrome

,

systemic mastocytosis

,

,

uveal neoplasms

,

squamous cell carcinoma of head and neck

,

t-cell lymphoma

,

transitional cell carcinoma

,

primary myelofibrosis

,

,

graft vs host disease

,

adenocarcinoma of lung

,

diffuse intrinsic pontine glioma

,

disease progression

,

oligodendroglioma

,

neurofibromatosis 2

,

acoustic neuroma

,

,

hodgkin disease

,

islet cell carcinoma

,

hematologic diseases

,

myeloid leukemia accelerated phase

,

,

mast-cell leukemia

,

,

germ cell and embryonal neoplasms

,

,

anaplastic thyroid carcinoma

,

t-cell lymphoma peripheral

,

waldenstrom macroglobulinemia

,

castration-resistant prostatic neoplasms

,

,

cholangiocarcinoma

,

chronic disease

,

large-cell lymphoma anaplastic

,

plasma cell granuloma

,

,

,

,

,

gouty arthritis

,

endocrine gland neoplasms

,

,

urogenital neoplasms

,

male genital diseases

,

prostatic diseases

,

abdominal neoplasms

,

male genital neoplasms

,

genital diseases

,

sjogren's syndrome

,

retinitis pigmentosa

,

,

,

giant cell tumors

,

pigmented villonodular synovitis

,

giant cell tumor of tendon sheath

,

choroidal neovascularization

,

pathologic neovascularization

,

hemangioblastoma

,

von hippel-lindau disease

,

inflammatory breast neoplasms

,

invasive hydatidiform mole

,

multidrug-resistant tuberculosis

,

local neoplasm recurrence

,

t-cell lymphoma cutaneous

,

peutz-jeghers syndrome

,

acute coronary syndrome

,

st elevation myocardial infarction

,

malignant mesothelioma

,

,

type 1 diabetes mellitus

,

,

intestinal neoplasms

,

testicular neoplasms

,

,

brain stem infarctions

,

,

sturge-weber syndrome

,

klippel-trenaunay-weber syndrome

,

neurofibrosarcoma

,

nerve sheath neoplasms

,

carcinoma in situ

,

breast diseases

,

multiple hamartoma syndrome

,

,

urologic neoplasms

,

fallopian tube neoplasms

,

t-cell leukemia

,

localized scleroderma

,

myelomonocytic leukemia chronic

,

myelomonocytic leukemia acute

,

myelomonocytic leukemia juvenile

,

,

,

ovarian epithelial carcinoma

,

sickle cell anemia

,

streptococcus agalactiae

,

colorectal neoplasms

,

myeloid leukemia acute

,

,

,

neoplasm metastasis

,

brain neoplasms

,

hepatocellular carcinoma

,

,

thyroid neoplasms

,

thyroid diseases

,

chronic urticaria

,

,

large b-cell lymphoma diffuse

,

b-cell lymphoma

,

,

triple negative breast neoplasms

,

,

colonic neoplasms

,

,

carcinoid tumor

,

pulmonary arterial hypertension

,

familial primary pulmonary hypertension

,

,

gastrointestinal neoplasms

,

stomach neoplasms

,

rectal neoplasms

,

,

meningococcal meningitis

,

meningococcal infections

,

rheumatoid arthritis

,

organ transplantation

,

graft rejection

,

digestive system neoplasms

,

cutaneous malignant melanoma

,

,

lymphangioleiomyomatosis

,

lupus nephritis

,

,

hypersensitivity

,

peanut hypersensitivity

,

multiple sclerosis

,

relapsing-remitting multiple sclerosis

,

interstitial lung diseases

,

,

lung transplantation

,

malignant carcinoid syndrome

,

serotonin syndrome

,

food hypersensitivity

,

psoriatic arthritis

,

,

muscular atrophy

,

spinal muscular atrophy

,

,

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

,

chronic inducible urticaria

,

infectious skin diseases

,

bacterial skin diseases

,

,

,

myeloid leukemia

,

,

bcr-abl positive chronic myelogenous leukemia

,

breast neoplasms

,

,

,

non-small-cell lung carcinoma

,

renal cell carcinoma

,

,

kidney transplantation

,

philadelphia chromosome

,

lymphoid leukemia

,

neuroendocrine tumors

,

gastrointestinal stromal tumors

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

myeloid leukemia chronic-phase

,

liver transplantation

,

renal insufficiency

,

tuberous sclerosis

,

chronic kidney failure

,

heart transplantation

,

kidney diseases

,

islet cell adenoma

,

,

,

macular degeneration

,

,

,

,

autosomal dominant polycystic kidney

,

communicable diseases

,

polycystic kidney diseases

,

,

diabetes mellitus

,

tick-borne encephalitis

,

,

immunosuppression therapy

,

cytomegalovirus infections

,

,

large cell carcinoma

,

vascular diseases

,

,

,

vision disorders

,

,

type 2 diabetes mellitus

,

cross-sectional studies

,

,

polyomavirus infections

,

cryopyrin-associated periodic syndromes

,

polycythemia vera

,

,

,

systolic heart failure

,

myocardial infarction

,

,

,

inferior wall myocardial infarction

renal insufficiency

,

,

hepatic insufficiency

,

immunosuppression therapy

kidney diseases

,

,

myeloid leukemia acute

,

,

myeloid leukemia

,

,

hepatic insufficiency

,

,

invasive fungal infections

,

,

communicable diseases

,

,

invasive candidiasis

,

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

,

,

lymphoid leukemia

,

,

respiratory insufficiency

,

,

giant cell arteritis

,

polymyalgia rheumatica

,

lupus nephritis

,

,

multiple myeloma

,

plasma cell neoplasms

,

,

,

,

,

pulmonary sarcoidosis

,

b-cell chronic lymphocytic leukemia

,

,

healthy volunteers/patients

,

obstructive lung diseases

,

,

graft rejection

,

thrombocytopenic purpura idiopathic

,

thrombocytopenia

,

,

interstitial lung diseases

,

thrombocytopenic purpura

,

,

nephrotic syndrome

,

,

,

,

follicular lymphoma

,

kidney transplantation

,

,

chronic obstructive pulmonary disease

,

liver transplantation

,

atopic dermatitis

,

,

,

graft vs host disease

,

chronic kidney failure

,

,

cytomegalovirus infections

,

communicable diseases

,

kidney diseases

,

,

renal insufficiency

,

heart transplantation

,

multiple sclerosis

,

,

chronic renal insufficiency

,

,

renal replacement therapy

,

drug-related side effects and adverse reactions

,

,

relapsing-remitting multiple sclerosis

,

vascular diseases

,

,

cystic fibrosis

,

allergic bronchopulmonary aspergillosis

,

pulmonary aspergillosis

,

transplantation

,

,

end stage liver disease

,

,

disease progression

,

healthy volunteers/patients

renal insufficiency

,

,

,

,

,

,

,

,

,

,

,

,

severe acute respiratory syndrome

,

,

coronavirus infections

,

,

vulvar vestibulitis

,

,

,

acquired immunodeficiency syndrome

,

,

,

immunologic deficiency syndromes

,

communicable diseases

,

,

healthy volunteers/patients

,

drug interactions

,

,

,

protein-energy malnutrition

,

hiv seropositivity

,

,

respiratory distress syndrome

,

acute lung injury

,

newborn respiratory distress syndrome

,

respiratory insufficiency

,

,

critical illness

,

hypercholesterolemia

,

,

,

,

,

postoperative complications

,

,

artificial respiration

,

,

,

,

treatment adherence and compliance

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